Loratadine
Loratadine (Claritin) is the preferred non-sedating second-generation antihistamine for pregnancy allergies. Multi-decade safety record with no consistent evidence of teratogenicity. Considered safe…
Niacinamide
Niacinamide (vitamin B3) is generally considered pregnancy-safe in topical skincare. The 'caution' rating reflects limited data on high systemic doses, not topical…
Octinoxate
Avoid octinoxate during pregnancy. The most-used chemical UVB filter globally, with estrogenic endocrine-disruptor signals in animal and cell studies. Flagged alongside oxybenzone…
Octocrylene
Use octocrylene cautiously during pregnancy. It degrades to benzophenone (a potential carcinogen) over time — particularly in older or heat-exposed sunscreens. Systemic…
Oxybenzone
Avoid oxybenzone during pregnancy. Endocrine disruptor that crosses the placenta. Studies link higher maternal urinary oxybenzone to altered birth weight and Hirschsprung…
Parabens
Use parabens cautiously in pregnancy. They have weak estrogenic activity, and some cohort studies link prenatal exposure to altered birth weight and…
Phenoxyethanol
Phenoxyethanol is pregnancy-safe at cosmetic concentrations (up to 1% in finished products). The FDA, EU SCCS, and Health Canada all accept it…
Phthalates
Avoid phthalates during pregnancy. This family of endocrine-disrupting plasticizers is associated with altered male reproductive development (reduced anogenital distance) and neurodevelopmental effects…
Pseudoephedrine
Avoid pseudoephedrine (Sudafed) in the first trimester and in anyone with hypertension. It's a vasoconstrictor that may reduce uterine blood flow. Older…