Acetaminophen
Acetaminophen (Tylenol) is the first-line OTC pain reliever and fever reducer in pregnancy per ACOG. Considered safe at recommended doses across all…
Adapalene
Avoid adapalene (Differin) during pregnancy. Although it’s a newer, third-generation retinoid with limited human pregnancy data, the class-wide retinoid teratogenicity caution applies.…
Aloe Vera
Topical aloe vera is pregnancy-safe with a long traditional and modern usage record. Soothing for sunburn, pregnancy itch, dry skin. NOTE: oral…
Avobenzone
Use avobenzone cautiously in pregnancy. The FDA Maximal Usage Trial confirmed it reaches plasma concentrations above the safety threshold after a single…
Azelaic Acid
Azelaic acid is FDA Pregnancy Category B — the strongest evidence base among topical acne and brightening actives. Effective for acne, rosacea,…
Bakuchiol
Bakuchiol is the leading pregnancy-safe alternative to retinol. A 2018 head-to-head clinical trial showed bakuchiol matched retinol's improvements in fine lines and…
Benzoyl Peroxide
Benzoyl peroxide is generally considered safe in pregnancy at low topical concentrations (under 5%, applied to small areas). Systemic absorption is around…
Calcium Carbonate (Tums)
Calcium carbonate (Tums) is the first-line antacid in pregnancy and is considered safe at recommended doses. It neutralizes stomach acid for fast…
Ceramides
Ceramides are fully pregnancy-safe. They are lipid molecules identical to those naturally in your skin's barrier — restoring rather than altering native…